Furthermore, supervised midwifery deliveries at home must be differentiated from low-skilled traditional birth attendant supervision.
In our VPCT study, we confirm the implication of our previous PCT published data, that high-grade gliomas can be differentiated from low-grade gliomas on the basis of CBV, CBF and Ktrans absolute values [ 1].
Despite the small number of patients with low-grade gliomas, our data implicate that high-grade gliomas could be differentiated from low-grade gliomas on the basis of all three PCT parameters studied.
High-risk lesions were differentiated from low-risk lesions with a sensitivity of 79%, specificity of 74% and an accuracy of 77%, cancer and normal tissue with a sensitivity of 79%, specificity of 83% and an accuracy of 81%.
The hyaline-vascular type of Castleman's disease which contains numerous lymphoid follicles should be differentiated from Hodgkin lymphoma and low-grade B-cell lymphomas [ 14].
This is because there is a poor correlation between signal intensity and target concentration at the low end [16], and because the signal obtained from these targets can't be differentiated from background noise in the low concentration milieu [22].
Thus, we speculate that since the down-regulation of CDKN1A and GDF15 is not as efficient as tRNA genes after Pol III knockdown, the amount of Pol III binding at CDKN1A and GDF15 prior to MAF1 knockdown may be too low to be differentiated from background (MAF1/Pol III knockdown).
The differential diagnosis includes tumour recurrence, which can be differentiated from ORN with DWI (high ADC values in necrosis as opposed to low ADC values in tumours).
Recent collapsed vertebral bodies show a low signal intensity on T1W images (oedema) and therefore cannot be differentiated from malignant infiltration.
