In addition, there appeared to be differential up-regulation of TRH expression in caudal parts of the striosomal system, judging from the immunohistochemistry.
We compared the baseline AUDIT-C scores, age and gender of participants lost to follow-up versus those followed-up to assess whether loss to follow-up was differential by randomization group.
We also carried out paired t-tests between the averaged pre-response and response volumes of the speed and accuracy conditions to determine whether there was differential build-up of activity in the two instruction sets.
Nevertheless, as this is a cross-sectional analysis of data collected at a follow-up phase of a cohort study, we cannot exclude the possibility that there may have been differential loss to follow-up related to these musculoskeletal parameters.
As part of these secondary analyses, we will also conduct a chi-square test to explore whether there is differential loss to follow-up between experimental conditions.
However, a cohort design may introduce bias if there is differential loss to follow-up at each wave and across clusters.
Other explanations for why there was no difference seen between intervention and control groups at the 6-month interval, as well as the modest difference at the 3-month interval, are differential loss to follow-up and the highly active control arms in this study.
While the main focus of the paper was differential acetylation profiling by bottom-up proteomics, our results are concordant with those (vide infra).
So what exactly is differential privacy?
A common feature between the mouse and human studies was the differential up-regulation of CXCL9 and CXCL11 in the older cohorts.
The major effect of rivastigmine, a combination of its activity against BUChE and the pseudo-irreversible cholinesterase inhibition, is the differential up-regulation of AChE and BuChE in the cerebral spinal fluid of patients after chronic treatment [ 80].
