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Regulation of kinase activity may be dictated by two components: a conserved Ser/Thr kinase activation component that results from autophosphorylation at Thr-474 and a novel inhibitory component at a distinct residue (Thr-469) within the A-loop that down regulates substrate phosphorylation.
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The strategy is dictated by two factors, ABC executives said.
The menu was dictated by two things: the market's offerings and the recipes in her forthcoming book, "The Art of Simple Food: Notes, Lessons and Recipes From a Delicious Revolution" (Clarkson Potter, October).
The fate of the cosmos is dictated by two forces.
Thus, nuclear dynamics are dictated by two fixed points, namely, the vector manifestation fixed point and the Fermi liquid fixed point.
Our simulations suggest that the solubility, solvation dynamics, and conformation of the oligomers are dictated by two factors: (a) the local structure of proximal water and (b) the diffusion and exchange kinetics of proximal water with bulk water.
Moreover, we found that the long-term fate of H7a-specific T cells was dictated by two host factors: thymic function and expression of H7a by normal host cells.
The choice of this cell line was dictated by two considerations; first of all, a transformed line is a tool that can be kept and used by several teams; second, JEG-3 cells are considered as a good model for trophoblasts, and have been used in numerous studies on this topic.
Our choice of a 2-year follow-up period is dictated by two factors.
The choice of this time horizon was dictated by two reasons.
The retrospective non randomized design of our study was dictated by two major issues: time constraints and acceptability.
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CEO of Professional Science Editing for Scientists @ prosciediting.com