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It will greatly facilitate the development of hESC-based therapy if new effective approaches can be developed to induce immune tolerance to hESC-derived allogeneic cells without long-term systemic immune suppression.
When such a collaborative relationship spans across multiple cultures, legal jurisdictions, and an extended period of time, the key boundary objects identified in this paper can be developed to induce a similar positive influence in a new context.
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Additional strategies have been developed to induce Cre expression specifically in activated, collagen-producing HSCs, even in an inducible manner.
A post-signal processing model is developed to induce pressure and shear stresses, respectively.
To enable the use of treated soils in railways infrastructures a specific test was developed to induce biaxial tension.
An eccentric shoulder exercise was developed to induce DOMS on neck/shoulder muscles using a specially designed dynamometer.
In the current work, a special fixture has been developed to induce polymeric resin into a surface fatigue crack in a cylindrical rod.
Based on the ability of TP53 to induce apoptosis, mitochondrial targeted TP53 fusion proteins have been developed to induce intrinsic apoptosis in cancer cells, which may be of relevance in adjuvant therapy for cancer treatment [201, 250].
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) has recently been developed to induce rapid liver hypertrophy to reduce the chance of post-hepatectomy liver failure in patients with borderline or insufficient future liver remnant.
Accelerated life time tests (ALTs) of on off cycle test with the duration time of 10 min and load cycle test with a voltage sweep of 0.6 V–1.0 V and a duration of 4.25 min, are developed to induce different stresses.
Peptide-based vaccines derived from the E7 protein of human papillomavirus (HPV) type 16 were developed to induce effective T cell responses against established cervical cancer, but have met with limited clinical success.
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