Sentence examples for be developed to bind from inspiring English sources

Its signalling functions do include ligand binding, and although antibody therapeutics can be developed to bind its extracellular domain and interfere with ligand binding, it is not clear whether the oncogenic functions of activated EGFR or HER2 are driven by extracellular ligands.

But it is the proteins that actually carry out bodily functions, and drugs are developed to bind to particular proteins.

Many of them have been developed to bind to folded proteins, yet cellular networks for signaling and protein trafficking often depend on binding to unfolded regions of proteins.

Recently, a technology was developed to bind growth factors to a fibrin matrix using the transglutaminase (TG) activity of factor XIIIa, thus allowing prolonged release through enzymatic cleavage.

It is true that many "atypical" antipsychotics have been developed to bind several sites within the brain.

The function of immunophilins is modulated by the FK506 family of ligands, several members of which have been developed to bind their targets without causing immune suppression.

Trastuzumab, a human monoclonal antibody was developed to bind the HER2 receptor and block its activity [ 6].

All three clones were developed to bind in vitro to IL-23 but their relative biologic effectiveness in neutralizing IL-23 was unclear.

Nevertheless, several small molecules have been developed to bind PPI sites with desired levels of affinity, yet they tend to be much larger, on average, than compounds targeting more classical binding sites and, as a result, exhibit much lower ligand efficiency (LE), i.e., binding free energy per heavy atoms.

An initial conceptual framework was developed to bound and guide the study.

Ideally, a computational model could be developed to predict whether a PRM will bind to a peptide given their primary sequences.