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Innovative trial designs are required that will allow a drug's effectiveness to be determined efficiently in the transition from normal to mild cognitive impairment to probable AD.
In typical applications of modal identifications, when there is sufficient amount of data, the formulation using the proposed mode shape scaling and parameterization scheme shows that it allows modal parameters to be determined efficiently in a globally identifiable manner.
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As discussed in the previous section, the sensitivity associated with the reliability analysis can be determined efficiently.
Taking into account the fact that the vast majority (43 out of 47) of the sd values lied in a range up to 0.12, we concluded that single copy number change can be determined highly efficiently in di- and triploid cells and less efficiently in tetra and pentaploid cells.
ACPA profiles can be determined most efficiently by using multiplex assays, in which multiple citrullinated antigens are tested simultaneously [ 18- 21].
In this paper, we have demonstrated, using the data of over 115 known drug molecules, that the nonspecific binding can be determined in vitro very efficiently using biomimetic high-performance liquid chromatography measurements.
Therefore, from such measurements the confluence in each well can be determined rapidly and efficiently.
Furthermore, the color distribution of any frame can be determined reliably and efficiently.
In order to generate HSCs from ESCs efficiently in vitro, optimal conditions must be determined for each developmental step in our model.
Hence, in a full-blown pro-inflammatory/pro-coagulant condition as met in sepsis, it remains to be determined whether platelet activation is efficiently inhibited by antiplatelet treatments.
Once big data is analyzed, trends can be revealed, correlations can be determined and business can run more efficiently.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com