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Because direct cell contact between chondrocytes and RASF was not provided, a genome-wide molecular response of chondrocytes to soluble synovial mediators could be determined by microarray analysis.
Pacing-induced alterations in the expression of other miRNAs with particular concern for their involvement in AF could not be determined by microarray hybridizations due to a high variability among replicates (miR-1, miR-21, miR-23a/b, miR-29a, and miR-133a) or very low hybridization signals (miR-10a, miR-10b; see the complete microarray data at NCBI through GEO accession number GSE65330).
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Advantages of sequencing include the direct determination of transcripts by RNA sequencing, and the fact that sequencing allows the discovery of new genes, while the genomic diversity that can be determined by microarrays is limited to the reference sequences used for array probe design.
Relative expression levels were determined by microarray analysis.
Samples were taken from different rice tissues as indicated in the left column and relative transcript levels in each tissue-specific transcriptome were determined by microarray analysis.
Samples were taken from different developmental stages as indicated and relative transcript levels of the entire transcriptome were determined by microarray analysis.
Finally, the off-target effects of all siRNAs were determined by microarray analysis using Illumina Beadchip technology.
Expression levels at each time point for each cell and treatment were determined by microarray analyses using the Illumina human Ref8v2 array.
To understand the molecular changes that result from Hdac3 depletion in osteoblast progenitor cells, the gene expression patterns in calvarial extracts were determined by microarray analysis and confirmed by qPCR.
To get an insight in the molecular origin of the differentiation blocks caused by OBF1 overexpression, the transcriptome of EPLM and large preB2 cells of each genotype was determined by microarray analysis.
In order to characterize the global gene activity correlated with each particular stage of neural development, the full transcriptome of different cell populations that arise during the in vitro differentiation protocol was determined by microarray analysis.
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