Mean arterial pressure, cardiac index, central venous pressure (CVP), and rSO2 at specific points were collected, and significant changes in each parameter were detected using repeated analysis of variance.
Preliminary data had suggested that MSH6-deficient tumours could be detected using mononucleotide repeats, but these studies were performed with a limited number of markers and tumours (Verma et al, 1999; Berends et al, 2002; Kets et al, 2006; Mead et al, 2007).
We therefore suspected that a large number of specific repeat types could not be detected using the existent repeat database.
To investigate the sensitivity of the cells to another PDT agent and confirm that neuronal death could be detected using this model, the experiment was repeated using hypericin.
Gene conversion between direct repeats can be detected using heteroalleles of a selectable gene, and can occur by intrachromatid or sister-chromatid interactions.
Simple and interspersed repeats were detected using Tandem Repeats Finder [ 50] and Repeat Masker, respectively, using the mammalian library along with cow-specific repeats submitted to EMBL/NCBI/DDBJ.
Tandem repeats were detected using Tandem Repeat Finder (version 4.04), and then classified using Tandem Repeats Analysis Program (version 1.1).
Sequences containing microsatellites were detected using Tandem Repeats Finder version 4.09 (Benson 1999), and primer pairs were designed for microsatellite loci with suitable flanking regions to amplify using FastPCR software version 6.5.94 (Kalendar et al. 2009).
Tandem repeats were detected using the Tandem repeat finder (Benson 1999) with the recommended settings, and a maximum period size of 500 bp.
Tandem repeats were detected using the Tandem Repeat Finder (v.4.04) developed by [ 67] with parameters (alignment parameters [match, mismatch, indel; 2,7,7], min. align. score 50; max. period size 2,000).
