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This reduction could also be detected in normal mice and C17.2 cells, indicating that this suppressive effect of brazilein was correlated with NOD2.
As both PCNA ubiquitination and NEDDylation could not be detected in normal cells, we performed immune precipitation (IP) to detect endogenous NEDDylation of PCNA in Nedp1 −/− cells.
Immunoblot analysis using specific antibody for PTMA clearly showed a single intense band of 12.5 kDa in whole cell lysates obtained from squamous cell hyperplasia (H1, H2), dysplasia (D1, D2) and HNSCCs (T1, T2) while no band could be detected in normal oral mucosa (N1, N2) (Figure 3b).
However, upon RT-qPCR analysis of the CNTNAP2 gene no expression could be detected in normal bone marrow samples, CD34+ cell fractions or EVI1 overexpressing bone marrow samples (data not shown), indicating that this gene is not a straightforward candidate 7q tumour suppressor gene cooperating with EVI1 overexpression.
CRT barely can be detected in normal SH-SY5Y cells.
As opposed to this, expression of MMP-11 could not be detected in normal breast tissue.
Similar(34)
The current investigation was undertaken to determine whether alterations of RUNX3 gene expression could be detected in normal-looking gastric remnant mucosa.
CXCL12 was detectable in the bronchoalveolar fluid in 40% of patients with interstitial lung disease, whereas none was detected in normal controls.
Hiwi expression has been detected in normal human testes and male germline malignancies, but was not detectable in ovaries (Qiao et al, 2002).
Results: By in situ hybridization, IL-8 mRNA was detected in normal glomerular, tubular, and some interstitial cells.
A high order hidden dynamic was detected in normal EEG records, confirming the very complex structure of the underlying system.
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