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These data show that (1) therapies can be designed to normalize ASL volume, without producing deleterious compositional changes in ASL, and (2) therapeutic efficacy will likely depend on development of long-acting pharmacologic agents and/or an increased efficiency of osmolyte delivery.
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Both logit and double-log methods are designed to normalize survival probabilities.
A coordinate system was designed to normalize the effects of applied variables and material properties.
A more recent study by Jones et al. [19] focused on comparing two early sepsis resuscitation protocols: one was designed to normalize central venous pressure (CVP), mean arterial pressure (MAP), and lactate clearance of at least 10%, and another with SvcO2 as a goal, as well as CVP and MAP, showed no difference for in-hospital mortality.
Unlike first-generation left ventricular assist devices, which were developed in the 1970s and were designed to totally capture the cardiac output, the Jarvik 2000 is designed to normalize the cardiac output by augmenting the function of the chronically failed heart for extended periods.
fRMA is designed to normalize large amount of heterogeneous microarray samples to reduce the effect of batch on gene expression estimates.
A new parameter for tumor sizing, tumor axial ratio (TAR), was designed to normalize tumor size by dividing ATA by RBS for each affected bone; thus, TAR represented the ratio of tumor axial size to affected bone axial size.
If a scorer is designed to normalize away these differences by taking into account the density of the spectrum prediction (as is the case for the HGT model), it can benefit from more accurate predictions.
A new parameter of tumor axial ratio (TAR) was designed to normalize tumor size by dividing the absolute tumor axial size by the reference bone axial size (RBS) of the affected bone.
A more recent study by Jones et al. [ 19] focused on comparing two early sepsis resuscitation protocols: one was designed to normalize central venous pressure (CVP), mean arterial pressure (MAP), and lactate clearance of at least 10%, and another with SvcO2 as a goal, as well as CVP and MAP, showed no difference for in-hospital mortality.
Our TbT method was originally designed to normalize tag count data for various scenarios including such biased differential expression.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com