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Our results can inform empirical studies that might be designed to demonstrate an abrupt shift in Taylor's law.
In addition to establishing safety and the maximum tolerated dose, first-in-human clinical trials should be designed to demonstrate target modulation, define the proposed mechanism of action, and evaluate pharmacokinetic-pharmacodynamic relationships of a new anti-cancer agent.
Since modulation of the putative target and the observed anti-tumor effects form the basis for the clinical development of a molecularly targeted therapy, early-phase clinical trials should be designed to demonstrate proof-of-mechanism in tissues of interest.
The Strauss test would be designed to demonstrate ship survivability.
3. Websites should be designed to demonstrate the educational effectiveness of their intervention, both on an individual and a programmatic level.
This protocol was the first interventional trial to be designed to demonstrate that CTC-driven management of chemotherapy improves the outcome of metastatic breast cancer patients.
Similar(51)
This extravaganza is designed to demonstrate the diversity and vibrancy of Muslim culture.
The composition was designed to demonstrate the usage of the words that are italicized.
Every phrase was designed to demonstrate that letting Labour back in would be tantamount to putting all the hard-gotten gains down the pan.
The campaign "was designed to demonstrate that he could make life difficult for them if he chose to do so.
Gerhard Schröder, the German chancellor, has just completed a trip to Washington that was designed to demonstrate that his long quarrel with Mr Bush was over.
More suggestions(16)
be designed to illustrate
seemed designed to demonstrate
be designed to implement
be designed to enhance
be designed to protect
be designed to accommodate
be designed to raise
be said to demonstrate
be designed to achieve
be designed to order
be designed to carry
be designed to maximize
be assumed to demonstrate
be designed to promote
be given to demonstrate
be made to demonstrate
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