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Exact(16)
Similarly, natural nonheme proteins can also be designed to bind heme in a manner consistent with the cytochrome binding motif.
For example, enzymes can be fused to zinc fingers or other programmable DNA-binding domains and RNA aptamers can be designed to bind enzymatic partners.
The small size of nanoparticles is especially advantageous in medicine; nanoparticles can not only circulate widely throughout the body but also enter cells or be designed to bind to specific cells.
This suggests that inhibitors could be designed to bind at this interface such as to prevent nucleotide-induced domain closure.
Netropsin and distamycin specifically bind to A/T-rich sequences, whereas lexitropsins may be designed to bind A/T- or G/G-rich segments.
Our system is modular and PBPs can theoretically be designed to bind most small molecules.
Similar(43)
In our efforts to abrogate DDX3 functions in vivo, we synthesized a small molecule inhibitor, RK-33, which was designed to bind to the nucleotide-binding site within the DDX3 protein and abrogate its functionality.
Most of the low molecular weight ADAM inhibitors use hydroxamate as the zinc binding group and were designed to bind to the MMP-like catalytic site [ 66- 69].
These observations suggest that the amine binding pocket of Ch-MAL (and Ct-MAL) is designed to bind small amine compounds and excludes large nucleophiles.
The agreement had been designed to bind investors in a common purpose, eliminating suspicion that they might betray one another.
One of the probes has been designed to bind to the silica backbone, while the other has been designed to bind to the transition metal species.
More suggestions(17)
be selected to bind
be predicted to bind
be used to bind
be created to bind
be designed to defense
be understood to bind
be breached to bind
be mutated to bind
be designed to box
be made to bind
be designed to grease
be exploited to bind
be reduced to bind
be shown to bind
be activated to bind
be expected to bind
be asked to bind
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