If these recommendations are followed, it is warranted that similar and useful information can be derived from trial reports, irrespective of the primary outcome measure used.
QALY data will be derived from trial data on EQ-5D-5L, using a UK algorithm/tariff, in the first instance those derived from Dolan 34 (via van-Hout et al 35; although it is expected that a UK tariff will be published at the time of analysis), for the 5-level EQ-5D).
All data on pneumococcal vaccination in patients with nephrotic syndrome are derived from trials with serological endpoints in children.
The SVR rates of SOF-based regimens for each patient disease stage were derived from trials and literature 29– 33 and validated by expert opinion.
Fifth, the effectiveness data were derived from trials lasting 8 16 weeks (atorvastatin) or 15 days–44 weeks (sevelamer), and these data may not be capable of extrapolation to the modeled period of 1 year.
Decisions regarding treatment should take into account that the evidence of benefit is derived from trials for which women were selected with a two step strategy (glucose challenge test/screening for risk factors and oral glucose tolerance test).
The evidence base that supports psychological interventions for depression, such as CBT [ 6], behavioural activation [ 7] and mindfulness [ 8] is derived from trials which have excluded individuals diagnosed with schizophrenia.
The RTs included in the analysis were derived from trials in which the participants responded correctly (8.9%% discarded) with an RT between 200 and 1,000 ms (less than 1%% of data discarded).
The clinical data used in this model were derived from trials of 6-month duration and therefore a limitation of the analysis is the uncertainty introduced in extrapolating these data to the 3-year base-case period and the longer time horizons assessed.
In our opinion proposals for screening for gestational diabetes have to take into account that some evidence of benefit of treatment is derived from trials for which women were selected by a two step strategy combining a glucose challenge test (or screening for risk factors, or both) and an oral glucose tolerance test.
