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Furthermore, the AML-initiating cells appeared to be derived from normal hematopoietic stem cells directly linking stem cells to tumorigenic cells.
CAFs are usually considered to be derived from normal fibroblasts (NFs) that are in close contact with tumor cells.
Libraries without a definite pathological description in the triplet were considered to be derived from normal tissues.
Cancer stem cells might be derived from normal stem cells in which specific tumor suppressor genes are mutated or lost [ 7].
Chang cells were originally thought to be derived from normal liver tissue, but subsequently found to have been established via HeLa cell contamination.
cfDNA can be derived from normal cells, including normal leukocytes that undergo apoptosis, and cancer cells; it is thus detectable in healthy volunteers, patients without cancer, patients with benign tumors, and cancer patients.
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Because tumors are derived from normal cells, most of the TAAs identified are self-antigens, and such TAAs are usually differentially overexpressed in tumor cells and are also expressed at a low level in some normal cells.
Other tissues were derived from normal individuals posthumously during autopsy after cardiac arrest.
Adult neurons were derived from normal temporal cortical samples removed during surgery for medial temporal lobe low grade glioma.
Expression of one or two endothelial markers on tumor vascular endothelial cells does not seem to sufficiently prove that they are derived from normal progenitors.
The human cells used in this report are derived from normal subjects or patients diagnosed with CDG Ia (PMM2 mutations: p.Ile132Thr/p.Arg123Gln [26]), CDG Ie [27], CDG Ig [28] and CDG Ih [22].
More suggestions(17)
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