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The results of the analysis suggest that the clinical benefits of bortezomib, in terms of response, delay in disease progression, and improved OS, could be derived at a reasonable cost [incremental cost-effectiveness ratio (ICER) $US45 356 per life-year gained], relative to thalidomide and BSC, in patients with relapsed refractory multiple myeloma.

Clearly, the higher acquisition cost of bortezomib compared with thalidomide and BSC is an issue but there is some evidence that the clinical benefits of bortezomib, in terms of response, delay in disease progression, and improved OS, can be derived at a reasonable cost in patients with relapsed refractory multiple myeloma.

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Within AlertsNet, quality indicators for the diagnosis and management of BSI will be derived at an institutional level and will be reported to the respective hospitals via web-based feedback for quality control.

Up to now, human embryonic stem cells have been derived at a later stage of development, when the embryo consists of about 150 cells.

Finally, a discounted cash flow value of $68.6 million for Mega Metallurgy Power is derived at a 1% terminal growth rate[19] (Table10).

A suitable Ni 5Zn film exhibiting smooth and dense surface was derived at a low current density of 0.067 ASD.

Although metrics were derived at a smaller scale (<1 ha) from partial plots, these may be unreliable due to the study design and possible confounding factors.

This condition, which is derived at a continuous level, has no adjustable parameters and is applied at the discrete level to couple the partitioned domain solvers.

The majority of onset detection algorithms consists of optional pre-processing stage, a reduction function (called onset detection function), which is derived at a lower sampling rate, and a peak-picking algorithm [21].

Figure 6 also demonstrates that the higher-Al/Si trend was derived at a higher pressure less than 200 MPa than the lower-Al/Si trend at a lower pressure.

Annual fire activity was derived at a 5 × 5 km resolution as a composite measure of active fire characteristics, including density and proximity of fires, annual duration of the fire season and range of FRP values.

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