Sentence examples for be dependent on activation from inspiring English sources

The bile acid glycochenodeoxycholic acid stimulated proliferation in a non-malignant Barrett's cell line in culture [ 42]: this effect was shown to be dependent on activation of the extra-cellular signal related kinase and p38 mitogen activated protein kinase pathways.

The pathophysiological functions of P2X7R are thought to be dependent on activation of this conductance pathway, yet its molecular identity is unknown.

These findings indicate that (1) angiotensin-(1 7) produces relaxation of canine middle cerebral arteries by the release of nitric oxide from endothelial cells, (2) angiotensin receptors do not mediate endothelium-dependent relaxations to the heptapeptide, and (3) this effect appears to be dependent on activation of local production of kinins.

If the increase in myostatin is viewed as a response to stress, then it may be dependent on activation of stress and/or growth pathways.

Indeed, a synergistic induction of microglial TNF-α and nitric oxide (NO) release was found to be dependent on activation of p44/42 MAPK.

It is, however, noted that attenuation of kainate-induced gamma oscillations in S100B KO [18] has recently been demonstrated to be dependent on activation of RAGE [13], suggesting a role of RAGE in hyperactive brain states.

Based on all these reports, it is suggested that the activity of angiostatic compounds is dependent on activation of NF-κB.

It has been stated that Src activity controls FGFR activation and FGF-2 induced AKT activation is dependent on activation of Src [51].

Mechanistically, SCFAs promoted Th1 cell expression of transcription factor Blimp-1, which is dependent on activation of STAT3 and mTOR.

These findings demonstrate that albumin-induced changes in gene expression are dependent on activation of TGFβ signaling pathways.

Furthermore, they provided evidence that the nitrergic IJP is dependent on activation of myosin light chain kinase.