Sentence examples for be demonstrated in large from inspiring English sources

In these cases, sometimes a regular lung sliding can be demonstrated in large peripheral blebs even if with some difficulty [34].

Beyond this, efficacy must be demonstrated in large multicentre clinical trials.

Thus, the ability of these agents to reduce vascular risk still needs to be demonstrated in large clinical trials.

The efficacy and safety of faster-acting insulin aspart need to be demonstrated in large clinical trials.

Whether these methods are more appropriate than MSP remains to be demonstrated in large cohorts of patients.

Before any single or panel of markers can be introduced as a reliable parameter for the evaluation of clinically relevant MD or MRD, their clinical significance must be demonstrated in large prospective cooperative multi-centre studies, performed according to SOPs.

The assumption that these new delivery systems should lead to an improved risk/benefit ratio in HT will need to be demonstrated in larger randomized controlled studies.

Therefore, the outcome of this study in a rat model of CPB remains to be demonstrated in large-animal and clinical studies.

The proof that prolonging infusion times will minimize the development of resistance is still lacking, and whether outcomes will be better must still be demonstrated in large-scale studies.

Currently, clinical correlations are limited and clinical importance including prediction of procedure outcome needs to be demonstrated in larger cross-sectional and longitudinal cohort studies.

Although the efficacy of MSC immunotherapy remains to be demonstrated in larger placebo-controlled trials, in several of the studies there were indications that the infusion of MSCs leads to immunomodulatory effects.