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A high specificity of the probe-receptor interactions could be demonstrated by blocking CCK2R binding positions with increasing concentrations of non-fluorescent, competitive minigastrin before addition of a fixed concentration of one of the optical probes.
The importance of integrin-mediated adhesion can be demonstrated by blocking it using RNAi.
Indeed, the sense of smell is of crucial importance for the perception and enjoyment of food, as may easily be demonstrated by blocking its function while eating.
The central role of TF in systemic inflammation could be demonstrated by blocking TF in Escherichia coli-induced septic shock, which increased survival in an animal model [ 30].
The precise role of GBF1 and PI4KB in the antiviral effect of curcumin may be demonstrated by blocking the down-regulatory effect of curcumin on these two proteins.
The importance of surprise for learning can be demonstrated by blocking – traditionally regarded as the canonical test of the involvement of associative mechanisms (Dickinson, 1981).
Similar(54)
The indispensability of the C-C loop for integrin binding has been demonstrated by blocking experiments using EDA-specific mAbsuchch as IST-9 and 3E2 which compromised the binding of EDA to α9β1 and α4β1 integrins and thus demonstrated that the C-C loop acts as a ligand for integrins10,11.
The specificity of uptake of both tracers was demonstrated by blocking with desipramine.
The importance of the S1P2 receptor in insulin resistance was demonstrated by blocking the receptor using a specific antagonist (JTE-013), thereby increasing hepatic insulin signalling [ 86, 109].
This was demonstrated by blocking IL-17 signaling that disrupted the CD4+ T-cell and B-cell interactions required for the formation of GCs [ 40].
The specificity of avidin biotin interaction was demonstrated by blocking the biotin residues on the tip with free streptavidin from solution.
More suggestions(15)
be demonstrated by setting
be demonstrated by painstaking
be stabilized by blocking
be influenced by blocking
be demonstrated by reheating
be attenuated by blocking
be targeted by blocking
be affected by blocking
be obtained by blocking
be demonstrated by comparing
be starved by blocking
be boosted by blocking
be stopped by blocking
be caused by blocking
be demonstrated by investigating
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com