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Non-inferiority is to be demonstrated based on a one-sided confidence interval with significance level of 2.5% for the difference between the two treatment arms.
It will be demonstrated based on a case study: the optimization of a multicomponent separation (lysozyme, ribonuclease A and cytochrome c on SP Sepharose FFTM), subject to pH conditions and optimal settings for the shape of the elution gradient.
Linearity of the measurement response can be demonstrated based on the fundamental understanding that a mixture is a linear combination of its components.
In 2007/2008, the authors carried out a randomized controlled pilot trial comparing ibuprofen and ciprofloxacin in uncomplicated UTI with regard to symptom course Non-inferiority of ibuprofen could be demonstrated based on a sample size of 79 patients.
In this study, the basis for selectivity of CDV for HPV+ tumor cells could be demonstrated based on analysis of drug incorporation into genomic DNA as well as gene expression profiling in HPV+ tumor cells, HPV- immortalized keratinocytes and normal keratinocytes.
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The underlying physical mechanisms critical to the device design are demonstrated based on very fast transmission line pulsing (VFTLP) measurement and physics-based simulation results.
An electro-optical modulator is demonstrated based on Fano-resonance effect in an out-of-plane illumination of one-dimensional slab photonic crystal composed of two graphene layers.
The approach is demonstrated based on an industrial example, the control software of an electro-mechanical braking system.
Mechanisms associated with the distinct memory effect were demonstrated based on the molecular simulation.
An all-fiber dynamic gain slope compensator is demonstrated, based on Mach Zehnder interferometer design.
Furthermore, the stability of the control algorithm is demonstrated based on the Lyapunov stability theory.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com