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Signal peptidase cleavage of prM protein results in the production of membrane-anchored forms of the C protein, which may be deleterious for replication if it functions poorly as a substrate for viral protease.
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High levels of dUTP can be deleterious for virus genomic DNA replication since dTTP can be substituted for dUTP during DNA synthesis [ 52].
Many argue that complying with the FBI could also be deleterious for tech businesses.
Nonetheless, at same time, such treatments were reported to be deleterious for electrical response of CNTs.
This property can be deleterious for tissue cells, especially when inflammation is sterile.
"Apparently they thought that this was deleterious for kids".
All of these factors are deleterious for cartilage integrity.
Even marginal hyperglycemia is deleterious for β-cells (17).
They share a high sequence homology and highly conserved RNA secondary structures, and mutations in the cDNA encoding the 5' UTRs would likely be deleterious to virus replication efficiency.
Corticosteroids likely influence inflammation associated with ADEM, but if ADEM is the result of a viral infection with persistent viral replication, steroids might be deleterious, allowing an increase in viral replication (8, 9).
These mismatches will give rise to mutations after a round of replication that can be deleterious or silent.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com