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Motivation and attention can be critical modulators of plasticity.
Salience, motivation and attention can be critical modulators of plasticity (Woldag and Hummelsheim, 2002; Nithianantharajah and Hannan, 2006; Kleim and Jones, 2008).
Numerous miRNAs have been found to be critical modulators of vascular pathologies, such as atherosclerosis, arterial remodelling, angiogenesis, and apoptosis [ 87].
There is good data that FcγRs may be critical modulators of inflammation within the synovium and that subtle changes in either expression or structure of these receptors may influence both the susceptibility to RA and the development of nodules.
Deregulation of phenotype switching and apoptosis of VSMC contribute to the development and progression of vascular pathologies like AA [ 35– 38], and miRNAs are found to be critical modulators of VSMC function (phenotype) such as cell differentiation, contraction, migration, proliferation, calcification, and apoptosis [ 39– 439.
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Innate lymphoid cells (ILCs) are critical modulators of mucosal immunity, inflammation, and tissue homeostasis, but their full spectrum of cellular states and regulatory landscapes remains elusive.
However, other subunits of the DHPR are critical modulators of both functions.
Noradrenergic (NA) neurons are critical modulators of brain functions and have been implicated in common CNS disorders [ 18].
C5a and its cognate receptor, C5a receptor (C5aR), key elements of complement, are critical modulators of liver immunity and fibrosis.
Mitochondria are an important source of ROS, molecules that are critical modulators of the synaptic pathology associated with aging and neurodegenerative disease.
CD22 and FcγRIIb are examples of B-cell-specific ITIM-containing surface receptors that are critical modulators of BCR signaling [ 7, 8].
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