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The chain length of the substitution at the 9-position was found to be critical in modulating the binding affinities.
Thus, the levels of these three proteins can be critical in modulating the quorum-response in P. aeruginosa.
Furthermore, the MAPK pathway was determined to be critical in modulating the activity of these embryonic protein(s) [ 14].
Here we report the expression of EMX2 during the early stages of CP formation, where the functions of this gene are thought to be critical in modulating arealization mechanisms (Cecchi & Boncinelli, 2000).
The unique profile of tolerability and antitumour activity of IDN 5390 is likely related to still unrecognised changes in drug cellular interactions that may be critical in modulating the toxic and therapeutic effects of taxanes.
Weitzman and Gordon found that the gene expression profile in metastatic breast cancer is very similar to the wound-healing process, therefore it is possible that the AR signaling in macrophages might be critical in modulating macrophages infiltration to tumor site and influence PCa metastasis.
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The immune system is critical in modulating cancer progression, but knowledge of immune composition, phenotype, and interactions with tumor is limited.
Here, we will first take a panoramic view of the liver from the angle of a lymphoid organ and discuss the composition and role of the immunological players that are critical in modulating between immune tolerance and immune responsiveness.
The ability of DNA and osmolytes in inducing conformational transition in α-synuclein, indicates that two factors are critical in modulating α-synuclein folding: (i) electrostatic interaction as in the case of DNA, and (ii) hydrophobic interactions as in the case of osmolytes.
Importantly, we find that Myc is critical in modulating the amplitude, whereas cyclin D/E activities have little effect on amplitude but do contribute to the modulation of duration of E2F activation, thereby affecting the pace of cell cycle progression.
The ILeak-Na conducted though the U-type channels is critical in modulating the rCPG rhythmic activity.
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Justyna Jupowicz-Kozak
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