Sentence examples for be critical for stem from inspiring English sources

The integrity of the PRC1 complex appears to be critical for stem cell maintenance.

In order to provide more major histocompatibility complex matched cell lines, HLA typing would be critical for stem cell-based therapies.

Recent studies suggest that stem cells are localized in the microenvironment of low oxygen [ 10, 11], indicating that hypoxia may be critical for stem cell maintenance.

It was previously reported that maintaining Oct-4 activity within a certain range appears to be critical for stem cell self-renewal, with any increase or decrease triggering differentiation to endoderm/mesoderm or trophectoderm respectively [ 12].

Recent work from Zhang and colleagues [ 61] has determined that a gene expression signature for a tumor-initiating cell population from a p53 mammary tumor knockout model is enriched for genes involved in DNA damage response and repair as well as for genes involved in epigenetic regulation previously shown to be critical for stem cell self-renewal.

Proper niche architecture is critical for stem cell function, yet only few upstream regulators are known.

The cell microenvironment, which is critical for stem cell maintenance, contains both cellular and non-cellular components, including secreted growth factors and the extracellular matrix1,2,3.

Accumulating evidence suggests that the mechanical and biochemical signals originating from cell cell adhesion are critical for stem cell lineage specification.

Furthermore, the use of ESCs typically causes ethical and immunorejection issues, and the elimination of these issues is critical for stem cell transplantation therapies to be effective.

Clonality is critical for stem cell research, and was accomplished in the microwell chips by isolation and clonal analysis of single mouse embryonic stem cells using flow cytometric cell-sorting.

Functional telomeres are critical for stem cell proliferation; however, whether they are equally important for the stability of stem cell differentiation is not known.