Sentence examples for be critical for stabilizing from inspiring English sources

Combined with our data, hydrophobic residues in this region of PcrV must be critical for stabilizing the structure.

Hydrogen bonding interactions between the flavin isoalloxazine- NH and either the amide portion of NADP or an amino acid side-chain appear to be critical for stabilizing the C4a-OO(H) against elimination of H2O2 or hydrolysis.

Moreover, β1-integrin-mediated attachment of brain endothelial cells to the basement membrane has also been reported to be critical for stabilizing claudin-5 localization at TJs and maintaining BBB integrity in vitro and in vivo[ 93].

Previously, we demonstrated that DA is critical for stabilizing the memory trace in a FPS paradigm [12].

According to Wiener's control theory, feedback is critical for stabilizing a dynamic system such as the hippocampal network.

This residue is critical for stabilizing the extrahelical εA complex.

Furthermore, ORCA is critical for stabilizing ORC binding to chromatin (Shen et al., 2010).

This demonstrates that the conserved side chains of Glu711, Glu712, and Ser715 are critical for stabilizing the binding of the CT domain to the motor domain.

Our results suggest that components of a signaling pathway involving GIT1, βPIX, Rac1, and PAK are critical for stabilizing surface and synaptic GABAARs and maintaining GABAergic synapse integrity in neurons.

These simulations allow us to obtain detailed atomic-level information about the dynamic behavior of the C-terminal domain interface of HIV-1 and its underlying driving force, which is critical for stabilizing the dimeric structure; in turn, these could allow us to identify pharmacological targets to block the capsid formation.

The D44 residue is critical for stabilizing proper KLF/SP DNA binding (Feng et al. 1994; Schuetz et al. 2011) and is notably absent from all nonfilozoan KLF-DBD motifs and the ctenophore sequence MleKLFX (supplementary fig. S1, Supplementary Material online).