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Fully understanding functions of ALT-PTK6 and its impact on PTK6 signaling will be critical for development of therapeutic strategies that target PTK6 in cancer.
Their main functions have been shown to be critical for development and differentiation.
Together, these studies suggest that Pin1-ΔNp63 α pathway may be critical for development of human squamous carcinoma.
In addition, the preschool period (at age 4-6) corresponds to the time of the adiposity rebound, which is thought to be critical for development of obesity.
Secretion of a polysaccharide adhesin is thought to be critical for development of a structured biofilm [ 84], although some biofilm-forming S. aureus strains cannot produce this polymer [ 85].
Therefore, both coding and regulatory sequences are expected to be under strong functional constraints for these genes and, particularly, for the Hox1 genes whose appropriate regulation has been shown to be critical for development (Kmita and Duboule 2003).
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"Those years are critical for development.
Infrastructure is another area that is critical for development.
These processes are fraught and complex, but they are critical for development and poverty reduction.
"Since the middle of the last century, we lost more than half of the salt marsh, which is critical for development of all of those species," he said.
They are critical for development and maintenance of epithelial architecture.
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be critical for developmental
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be valuable for development
be responsible for development
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be eligible for development
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