Sentence examples for be critical for binding from inspiring English sources
Iron-regulated surface determinants (Isd) of S. aureus are known to be critical for binding, uptake and utilization of heme from host proteins [10], [11].
The complexity of Harakiri NMR spectra precludes the identification of residues directly involved in the interaction, and thus residues 22 53 (Hrk_medium), which are known to be critical for binding from the NMR and ELISA data, were all input as participating residues in the docking protocol.
The SEA motif was previously shown to be critical for binding GIPC1 (Wang et al., 2006).
Our results indicate that SOX4-Lys95 isupposeded to be critical for binding to target genes and transcriptional activity.
The results from the present study have identified the histidine located at the fifth position of the N-terminal end of HKII to be critical for binding to the MOM.
The last three amino acid residues, including leucin at position 246 (245 in spinach), were shown to be critical for binding to PSII and for restoration of oxygen evolving activity [ 47].
In the present study, we identified specific structural features in flavonoids that were critical for binding to transferrin.
K1487, with 79% persistence, was a false negative (i.e., it is critical for binding despite having a lower contact persistence).
Structure-based mutagenesis defines three sites in β-catenin that are critical for binding the Tcf3-CBD and are differentially involved in binding APC, cadherin, and Axin.
Pharmacophore is the 3D orientation and spatial arrangement of functional groups that are critical for binding at the active site cavity.
