To test the feasibility of the approach, CPY* deletion variants were created systematically to eliminate a potential export signal (Fig. 1A).
Such heterotic groups as the basis of sustainable hybrid breeding need rather to be created systematically, by building on existing combining ability patterns and aiming to maximize combining ability between the groups.
Moreover, a possible limitation of the study is the percentage of missing values ranging from 0.4% to 35% in different variables without having any indication that they were created systematically.
The added value that could be created by systematically using genebank material, cannot be estimated highly enough.
In accordance with the Spanish Law on Equality, the experts considered that a consensus document should be created that systematically supports compliance with the necessary requirements throughout all stages of the development plan of a new drug, including publication of results.
Other resources have been created to systematically compare the influence of the genome on aging processes.
In 2000, a reference center was created to systematically record leishmaniases in Germany.
A number of databases have been created to systematically store the drug-target interactions such as SuperTarget [ 10], Psychoactive Drug Screening Program (PDSP) [ 11], Drug Gene Interaction Database (DGIdb) [ 12], and STITCH ('search tool for interactions of chemicals') [ 13].
A data extraction form was created to assist in systematically identifying main themes, methods, study design and setting.
Forty-one distinct three- and four-part mixtures were created with systematically varied functionality, chemical structure, type and concentration of crosslinker.
