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They need to be converted into functional polymers and materials by various technologies, including chemical reactions, fermentation, and modifications.
Here, we show that human ESCs and iPSCs can be converted into functional iN cells with nearly 100% yield and purity in less than 2 weeks by forced expression of a single transcription factor.
The cells can readily be converted into functional hepatocytes in vitro and upon transplantation in vivo.
Recent studies have also shown that fibroblast cells can be converted into functional neurons [ 19].
Recent studies demonstrate that Sertoli cells can be converted into functional neural stem cells.
Lineage tracing studies in vitro as well as in vivo have clearly shown that rodent acinar cells can be converted into functional beta cells [ 14- 17].
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Instead of merely forming scars, the fibroblasts in the heart were being converted into functional, beating heart cells -- cellular alchemy with great promise for new cardiovascular therapies.
The Recon 1 can be converted into a functional in silico model can be converted into a functional model of human metabolism, which was validated by applying 288 flux balance analysis (FBA) based tests of core functionality of human metabolism [ 17].
Importantly, the vinyl pyridine moiety can easily be converted into other functional groups.
Therefore, a detailed reconstruction of mouse metabolism that can be converted into highly functional model is of a great importance.
In addition, they can be converted into other useful functional groups by reaction with appropriate nucleophiles [29] and used as carbonyl surrogates for asymmetric synthesis [30].
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