Adipocyte differentiation is controlled by differential expression of C/EBP and PPARγ proteins (Park et al., 2012).
Hence, co-occurrence among reseeders may be controlled by niche differentiation along life-history axes associated with time to maturity, or environmental gradients such as soil fertility, which influences growth rates [ 22].
Neuro2a cells are a murine neuroblastoma cell line that has proven to be a useful experimental model for studying some aspects of differentiation mechanism since its differentiation can be controlled by various conditions, such as low serum concentration, retinoic acid and cAMP [ 26, 27].
This study shows that in MC3T3 preosteoblasts focal adhesion kinase (FAK) Y397 phosphorylation, cell spreading, and osteogenic differentiation can be controlled by RGD nanopatterning, with the distribution of islands throughout the hydrogel (i.e. how closely spaced the islands are) being the most significant pattern parameter.
While mutations and other genetic alterations can speed up cancer cell growth at a certain degrees of metastasis, the amount of EMT defining a particular degree of differentiation should be controlled by epigenetic changes [17].
Our study also indicates that cell proliferation and differentiation might be controlled by the applied strain.
The transcriptional targets described here represent enticing mechanisms through which PC12 cellular differentiation may be controlled by activated p53.
Therefore, apoptosis in cells escaping from terminal differentiation might be controlled by an unknown mechanism of p53 activation.
This network model contains gene regulatory events following the stimulation with two distinct chondrogenic factors, therefore providing a view on how genes involved in differentiation might be controlled by external molecules.
In teleostean fish, sex differentiation can be controlled by in vivo treatments with sex steroids (reviewed in [ 1]) as in reptiles and amphibians and to some extent in birds (reviewed in [ 2- 4]).
