Sentence examples for be context dependent with from inspiring English sources

Curiously, their impact appears to be context dependent with INK4a playing the predominant role in human cells and Arf assuming greater significance in mouse cells [10], [19].

Since MEK inhibition largely ablates S405/418 phosphorylation, the impact of PAK1 activity on S405/418 phosphorylation may be context dependent, with direct PAK1 phosphorylation of cortactin S405/418 regulating actin polymerization required for endosomal trafficking in contrast to impacting lamellipodia actin dynamics.

Such results suggest that predictors of readiness may be context dependent, with some variables being important for only some changes in some organizations.

The importance and route of apoptosis-driven mechanisms may prove to be context dependent, with variation between tumor types (and perhaps individual tumors).

Previous functional categorization has occasionally relied on sequence homology, but receptor-ligand affinity can be context dependent with receptors activated by multiple classes of hormones from heterologous taxa.

In a dynamics governed by interactions, the organization of the components and the way they process information are context dependent, with no particular function being encapsulated in any of the components themselves.

Bozkulak et al., demonstrated that although Notch1 was a substrate for both ADAM10 and ADAM17, the specific protease required for NICD activation was context dependent, with ADAM10 absolutely required for Notch1 signaling in response to Notch ligands, while ligand-independent activation was regulated by ADAM17 (Bozkulak and Weinmaster, 2009).

Furthermore, many interactions are context dependent, with the direction and magnitude of effects conditional on host genetics,, the environment and abundances of other microbiota.

One could speculate that the mode of RNA binding by FUS is context dependent with respect to the RNA and cellular condition.

We show that continued interaction between IBS2 and integrins is context dependent, with lack of IBS2 proximity to integrins at MASs, as in focal adhesions [ 13, 14], and retention of proximity in the wing.

The near-extinction of native digging mammals from much of Australia is likely to have significantly altered termite activity and decomposition, but impacts may be context-dependent, with aridity potentially playing a key role.