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Unlike tumor biopsies that can be constrained by problems such as sampling bias, circulating tumor cells (CTCs) are regarded as the "liquid biopsy" of the tumor, providing convenient access to all disease sites, including primary tumor and fatal metastases.
Unlike tumor biopsies that can be constrained by problems such as sampling bias, CTCs are regarded as the "liquid biopsy" of the tumor, providing convenient access to all disease sites, including the primary tumor and fatal metastases.
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However, their implementation is constrained by problems of discriminating relevant signals from non-specific reactions and bulk concentrations.
These southern irrigation schemes are most viable, and expansion related to the Kavango, Zambezi and Kunene river systems in the northeast and northwest broad integrated regions will tend to be constrained by financial and economic viability problems.
Yet Mr Tsang argues real elections could free the DAB of an association that puts off many voters, and allow it to exploit its formidable local network and strength on bread-and-butter issues.Even if most of Mr Tsang's colleagues agreed with him, which they do not, the DAB would be constrained by what he calls its "20-80" problem.
Ought theatre be constrained by ethical considerations?
Don't be constrained by the boxes.
Drewett has been constrained by unresolved problems with his vocal chords, which often left his voice a hoarse whisper and forced him to consider surgery to address the problem.
The interviews with providers revealed their awareness of the compromised quality of care, but they were constrained by structural problems.
Moreover, the estimation of life expectancy is constrained by technical problems of unreliability of data, especially pertaining to the older age groups (generally more than 65 years) in the developing countries (25).
Studies looking at adherence to r-hGH treatment have been constrained by the problem of recording adherence, but results have shown that non-adherence is a problem in some patients [ 4- 7].
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