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The targeted fractions, sequential extraction reagents and conditions are shown in Table 2. Three modifications are made compared to the original procedure proposed by Tessier et al. [43] to be consistent with methods used by Koretsky et al. [12] and to allow the use of small quantities of sediments.
However, to be consistent with methods in the literature and to make our gene expression results comparable with previous studies, we treated a different set of fish (n = 18) with racemic fluoxetine for two weeks.
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Rates reported as proportion of total number of doses given, to be consistent with method of reporting used in existing literature.
Such identification was consistent with methods previously reported in the literature [ 13, 20].
In the absence of a straightforward and internationally agreed approach to an alternative reference standard at present, we believe that this is the most robust approach and is consistent with methods currently used in independent HTA clinical studies in this setting.
Our findings of a substantial FAO overestimation of individual-level dietary intakes for most food groups were consistent with methods used to generate FAO data, which were developed to capture food availability rather than actual intake, do not account for all sources of waste (4), and can underestimate the resident population used to calculate per capita values (14).
For consistency with methods used in PCAT studies in other countries, we assigned a median value of 2.5 to "not sure/don't remember" answers, to be consistent with the methods used in PCAT studies in other countries [ 17].
In order to be consistent with filter methods, the size of subset in feature selection was also optimized using a cross-validation scheme.
The form of PEI rate-law expression should be consistent with the method for calculating the overall PEI of mixtures of chemicals inside reactors.
We show that the control mode intervals used in the Basic method are too narrow to be consistent with the Extended method.
The experimental design should also be consistent with the intended method of statistical analysis [ 30].
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