Three different in situ stress contrasts between pay zones and barriers are considered when simulating and analyzing the separate layer fracturing process.
The possible overestimation of rice yield should thus be considered when discussing the simulated future yield.
Differences in body weights of subjects in the phase I and III studies should be considered when a model developed with mostly normal weight subjects is used to simulate into a new and obese population.
Table 1 gives a summary of all variables considered when simulating patient data and the values chosen for these.
Significance was considered when P<0.05.
Sensitivity analysis for inhibition constant (Ki), fraction unbound in plasma, microsomes and gut (fup, fumic, fugut, depending on the gastrointestinal model utilized), and permeability is considered crucial when simulating the impact of a possible CYP3A perpetrator on the PK of a victim drug.
Similarly, patients were considered non-adherent when simulated atazanavir plasma concentrations were below MEC.
When equilibrium sorption was considered, the simulated profile of trifluralin in each domain was similar; however, the atrazine profile was deeper in the PFD than in the bulk matrix under episodic storm events.
When only the two oldest age classes were considered, 61 simulated datasets estimated N e > 1000.
The simulated future growth can be considered as an untreated virtual control (UVC) when compared to a patient's treated tumor.
