The two principal cannabinoid receptors (CBRs) 1 and 2 belong to the class-A GPCR subfamily and are considered tenable therapeutic targets for several indications.
By his action, Franjo Tudjman, the Croatian President, has sent a signal that he has little or no use for the United Nations, whose mandate is considered tenable only if diplomatic, rather than military, avenues are used to resolve the conflict in Croatia and Bosnia.
It now seems that no simple view is tenable and combinations of effects must be considered.
The Christchurch-based Super Rugby club, the Crusaders, have confirmed a name change and rebranding will be considered in the wake of the terrorist attack on two mosques, with the status quo "no longer tenable".
This theory is not considered tenable by most commentators.
Bluntly, the permanent secretary should be considering whether his own position is tenable, and so should the former transport secretary Justine Greening and her former minister of state, Theresa Villiers.
The first constraint, even though it is known to not be tenable in many cases, is considered as a prerequisite while dealing with GRNs.
Historically, ER, PR, and HER2, where available from the primary cancer, have been used to direct subsequent therapy, assuming no change in the biological features of the recurrent disease compared with the original primary; this approach is no longer considered tenable [ 3, 4].
Bush's top advisers are considering whether it is tenable for Rove to remain on the staff, given that Fitzgerald has already documented something that Rove and White House official spokesmen once emphatically denied -- that he played a central role in discussions with journalists about Plame's role at the CIA and her marriage to former ambassador Joseph C. Wilson IV, a critic of the Iraq war.
