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In this article, we present a discussion of the factors to be considered in initial activity studies, followed by a specific example of early clinical assessment of a noncytotoxic agent (R-flurbiprofen, E-7869) as a potential chemopreventive agent for prostate cancer.
However, the foundational properties and basic constraints might influence the entire system more than the quantifiable elements and have to be considered in initial analysis steps.
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A PIF2 system analogous to the HIF2 system was considered in initial tests, but was eliminated from final testing because the PIF2 approach performed badly in an informal experiment, as compared with the other approaches.
NRCS accepts applications for EQIP on a continuous basis, but producers must file applications by the deadlines below to be considered in these initial ranking periods.
The inability of the European Union as a whole to issue specific licenses and exemptions to sanctions policy means that such exemptions must be considered in the initial design.
Furthermore, because it is unlikely for spinal cord neoplasm to present acutely, an acute presentation may signify metastatic disease and should be considered in the initial differential diagnosis.
However, the low allele frequencies for ARR should be considered in the initial stages to prevent possible bottlenecks in future genetic progress.
To be considered in our initial course assignment process, applications must be received by 11 59 p.m. Eastern on January 25.
The presence of hypothermia or hyperthermia should be considered in the initial treatment of the patient with traumatic injuries.
The presence of hypothermia or hyperthermia should be considered in the initial treatment of the patient with traumatic injuries and corrected to the normal range of 36° to 38°C.
Numerous metabolic and physicochemical aspects about AS had to be considered in the initial model building.
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