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The step size can be considered at random during the initial stage of estimation.
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The simulation of a trajectory started with the two proteins (two adjacent chains of CtxB5 are considered) at uniformly random orientations at a center-to-center separation distance b, and finished when the protein centers reached a separation distance c greater than b (b = 100 Å, c = 500 Å).
Algorithmically, directed migrations are considered at the same frequency μ as random migrations, where μ = 0.00635 mm h-1 or about 15 lattice moves (cell widths) per day [ 15].
The marginal model expresses averaged relationships without taking into account the fact that the same subjects are considered at each time point, whereas the random-effects model gives relationships conditionally on having certain individual characteristics modelled by the random effects.
All model factors were considered as random.
All factors were considered as random effects.
Subject was considered as random effect.
However, major selection bias is unlikely, as the choice of an alternative biotreatment is currently still essentially a matter of the physician's personal preference (there are no 'treatment guidelines' for Swiss rheumatologists) and can thus be considered largely at random.
Only points in the spatiotemporal neighborhood of the target point defined by the ranges in the spatial and temporal domains need to be considered for random number generation at the target point A. Note that the spatiotemporal neighborhood changes with the target point.
Nobody cared that its accuracy could at best be considered random.
By using mixed model analysis, unequal use of the devices will not necessitate correction, as long as missing data can be considered to be at random.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com