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Almost 80% of the potential CFS fulfil the second CFS criterion (see Table 1), which means that they meet two of the criteria to be considered as persistent (P), bioaccumulative (B), and/or toxic (T), as defined under point 3.7.2 of Annex II to the PPP Regulation.
Finally, after testing these 48 transcripts, 12 could be considered as labile transcripts with a minimum fold decrease of −2.65 log10 (value arbitrary chosen), and 11 of them could be considered as persistent transcripts with a maximum fold decrease of −1.75 log10.
A symptom will be considered as persistent if it was present on at least two subsequent assessments, regardless of time of first manifestation of the symptom.
In addition, another pulsotype (T1), which cannot yet be considered as persistent, was found in drains of a cheese factory (FBO 12) at times four months apart (March to July 2013).
For patients in the PMX group, the treatment persistence was based on PMX use; patients could switch between different types of PMX (aspart or lispro) during the follow-up period, but would still be considered as persistent users of PMX.
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An event was considered as persistent disease or reappearance of documented locoregional/distant disease or disease progression with increase in the serum Tg levels and/or demonstration of structural/functional lesions.
Work exposure was considered as persistent when the patient continued working with the same job title and in the same environment, whereas it was considered as reduced when the patient had been relocated in another area of the same factory where the specific sensitiser was not used, with occasional short-term direct exposure to the specific sensitiser.
Hence, M1 has to be considered as very persistent in the environment.
Among the number of chemical compounds used in cosmetic products, some with a high lipophilicity (log KOW > 6) and low biodegradability (not ready biodegradable) may be considered as potential PBT (persistent, bioaccumulative, toxic) or vPvB (very persistent, very bioaccumulative) substances as defined in REACH, Annex XIII [6].
The present clinical case report suggests that AN may be considered as source of persistent pain in TMD patients and, therefore should be considered in the differential diagnosis or as a comorbid condition, as in the case presented.
The latter finding is consistent with the fact that auto-antigens can be considered as chronic and persistent antigens and in line with observations that re-stimulation of the TCR on activated T cells is required to drive expression of FasL triggering autocrine T-cell suicide or fratricide.
More suggestions(15)
be regarded as persistent
be considered as rude
be characterized as persistent
be treated as persistent
be considered as language-insensitive
be considered as nonspecific
be considered as non-breaking
be considered as preliminary
be defined as persistent
be considered as positive
be considered as cut-off
be considered as ellipsoid
be considered as confirmed
be designated as persistent
be identified as persistent
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com