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DOI: http://dx.doi.org/10.7554/eLife.06181.017 Conversely, evolution of a hypothetical enzyme in which each active site residue provides an independent rate advantage would be considerably more probable, as addition of those residues would lead to monotonically increasing catalysis (i.e., be continually uphill on a fitness landscape and thus selected for after each addition).
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Cardiff might actually go to Anfield and win 2-0, they concede, but overall it is considerably more probable that they will lose 8-0.
The rule in Portugal appears to be considerably more flexible.
There needs to be considerably more work done.
"There might be considerably more support for the decision".
But Serge Mackowiak, the French deputy public prosecutor, was considerably more cautious, saying it was "highly probable" that the wing flap came from the doomed flight.
"We are considerably more optimistic".
The reality is considerably more fraught.
There was considerably more to appreciate.
For Italy things are considerably more equivocal.
His start Saturday was considerably more arduous.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com