Sentence examples for be considerable difficulty from inspiring English sources

However, in high-prevalence countries there may be considerable difficulty in using this technique, as an insufficient proportion of cases may be captured for testing [ 6].

Banks reported no major problems today, and the financial markets were closed, masking what could be considerable difficulties whenever they reopen.

These divergent perceptions suggest that there may be considerable difficulties when perception surveys are used to quantify 'benefits' following environmental improvement programmes.

In many cases, however, there proved to be considerable difficulties translating agreed principles into practical proposals.

But in fact he holds that there is considerable difficulty in making sense of the doctrine.

However, due to the complex interactions and overlap of anatomy and physiology, there is considerable difficulty associated with determining the contributions of structures involved.

However, there has been considerable difficulty in developing an efficacious malaria vaccine, highlighting our incomplete understanding of immunity against this disease.

However, standardized commercially available reagents do not exist, and there is considerable difficulty distinguishing closely related species [13].

Moreover, there is considerable difficulty in interpreting the published data regarding prehospital intubation, since the relevant studies frequently have very dissimilar populations that also receive dissimilar care.

There is considerable difficulty, however, in using HGVS for the well-known deletions including those found in the GJB6 gene (http://www.hgvs.org/mutnomen/uncertain.html exondel).html exondel

There are considerable difficulties with an "evidence-based" approach to bioethics, however, that require consideration.