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Although the limited available data prevented us from making statistically significant observations, we note five H2H mutations (in the NP and PA proteins) that have appeared over several decades and may be conserved in circulating adapted strains.
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- Similarly, H7N9 epitopes that are conserved in circulating seasonal influenza strains may contribute to recovery from infection.
mAb 3791 is largely subtype C restricted, but because this subtype represents 50% of the disease pandemic, the neutralization epitope targeted by 3791 is estimated to be conserved in 63% of circulating strains worldwide.
A total of 609 of the remaining 946 putative class I epitopes, spanning the internal proteins, were found to be conserved in one or more of the circulating 2012 2013 influenza A strains.
These patches of conserved amino acids tend to be conserved in humans as well.
# Matrix size: resolution * matrix should be conserved in each dimension.
Energy will always be conserved in relativistic theories.
You have to conserve all the quantum numbers that need to be conserved in every interaction that takes place.
mAbs 2219, a subtype B derived mAb, and 2557, a non-subtype B derived mAb, are conserved in 56% and 52% of circulating strains worldwide, and are relatively evenly conserved across the major subtypes.
Conversely, 83 of the 84 putative epitopes derived from internal H7N9 proteins are conserved in at least one of the currently circulating influenza A strains.
Multiple (six) water (negative) controls were included in every run to detect low level contamination and a PCR to amplify a sequence that is conserved in most murine leukaemia viruses was included in order to expose any circulating MLV contamination and to detect any variant of XMRV that might be circulating in the UK CFS population.
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