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Tissue regeneration declines with aging throughout the old body, suggesting that the age-specific regulation of organ stem cells might be conserved between multiple organs.
Here target sites that appear not to be conserved between multiple species are filtered out from the search results, removing false positives, and leading to increased specificity.
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Here we have identified several PDE4 splice variants from the gene isoforms that are conserved between multiple species clades.
As expected, conservation of TFBS decreased as species became more evolutionarily divergent [ 40], so those TFBS that were conserved between multiple species including opossum are more likely to be functionally important in the regulation of gene expression.
Genes such as this, which are conserved between multiple CI-inducing strains (WD0622 has two orthologs in the CI-inducing wRi strain) but disrupted in a non-CI strain, are prime candidates for involvement in CI.
Four of the five alignment positions in which multiple putative functional residues are conserved between Hmd enzymes and paralogs cluster into a single distinct region.
Some EREs that were conserved between mice and humans were perfect matches, whereas others had multiple mismatches in their two half-site.
Here, we use murine cells to establish that this chromatin signature is conserved between mouse and human and is associated with MAE in multiple cell types.
14 15 However, the success of T cell vaccines in regions where multiple HCV genotypes coexist will depend on the generation of T cells that have the capacity to target multiple viral strains or viral regions that are conserved between genotypes.
Multiple H-bonds constrain and stabilize the cysteine ligands, which are conserved between most bc1 and b6 f Rieske proteins.
Multiple sequence alignment of the PCR products revealed that the polymorphic variations were conserved between Pi2 and alleles of the other 23 tested cultivars (Fig. 2b).
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