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To diagnose the rare CZ PCa, asymmetry at T2W should be confirmed in multiple planes and corresponding functional imaging findings such as increased signal intensity on long b value trace EPIs and/or suspicious contrast kinetics at DCE are helpful, as these latter findings are not expected in the normal CZ (Fig. 2).
vanEngelsdorp and Pettis are not yet sure this is a real effect; good science requires that results be confirmed in multiple studies.
Therefore, putative associations identified by GWAS must be confirmed in multiple large cohorts.
Few allelic variations associated with MS severity have been found, and the only one to be confirmed in multiple studies is the association between increasing allele load of HLADR15 and lower age at MS onset [2], [7], [8], [9], [10].
The results could be confirmed in multiple further trials (Al-Batran et al, 2011, 2012).
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And even studies that have been peer reviewed should be viewed with a certain amount of skepticism until they have been confirmed in multiple subsequent studies and stood the test of time.
The various approaches that have been used to address the question of IF DP interactions have provided data that are frequently in agreement, but differ in certain areas, for example, the importance of the flexible C-terminal tail in DP has been confirmed in multiple studies.
The drug has now been confirmed in multiple places in Ontario: St. Thomas, Cambridge, Kitchener.
All trends established in this research were confirmed in multiple groups, for example the difference between FDA-approved anti-cancer tandets and random genes was supported by the difference between proposed anti-cancer targets and random genes.
Lack of cross-resistance between anthracyclines and taxanes have been confirmed in multiple studies [16], [17]; thus, potential salvage by second-line therapy may have significant influence on subsequent relapse-free as well as disease-specific survival, masking a potential correlation between response to first-line treatment and RFS and/or DSS.
These results were confirmed in multiple experiments.
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