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Whether susceptibility for other cardiomyopathies, such as dilated cardiomyopathy, can be conferred by mutations in JPH2 warrants investigation.
Fluoroquinolone (FQ) resistance in Mycobacterium tuberculosis can be conferred by mutations in gyrA or gyrB gene.
Notably, it has been shown that tetracycline resistance can be conferred by mutations in RpsJ [ 45, 46].
Because the spiroindolone chemotype is structurally different from the aminopyrazole class, we did not expect resistance to both chemical classes would be conferred by mutations in the same gene.
Mutations in the QRDRs of gyrA and parC are the most commonly documented quinolone resistance mechanisms, but resistance is also known to be conferred by mutations in the second topoisomerase gene, parE [ 14].
It has been shown that a selective cellular growth advantage can be conferred by mutations in the mitochondrial genome that can result not only in a high level of heteroplasmy but also homoplasmy for the mutation (Polyak et al, 1998).
Similar(53)
In every case, resistance is conferred by mutations in existing genes, not by the acquisition of new genetic material.
A dominant form of obesity is conferred by mutations in MC4R that lead to a reduced receptor function e.g., [ 85– 91].
In addition, on-going analysis of four proanthocyanidin variants suggests their novel phenotypes are conferred by mutations affecting previously uncharacterised genes, based on diallelic crossing with known mutants and molecular characterization of the insertion sites (data not shown).
This can be conferred by point mutations or gene amplification events.
Furthermore, the lack of preneoplastic lesions suggests that clonal expansion of cells with growth advantages (such as can be conferred by Kras mutations) were not present.
More suggestions(15)
be reverted by mutations
be incurred by mutations
be deleted by mutations
be conferred by institutions
be disturbed by mutations
be rescued by mutations
be altered by mutations
be tested by mutations
be bypassed by mutations
be maintained by mutations
be mediated by mutations
be stabilized by mutations
be blocked by mutations
be initiated by mutations
be conferred by P450s
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