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Read-across assessments will be conducted using available in vivo test data as their primary basis; in a second step, novel in vitro and in silico data will be integrated and the read-across assessment repeated.
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Validation analyses were conducted using available permanent GNSS stations in the studied area.
ParaHox gene searches were conducted using available genome databases.
This study was conducted using available bioinformatics tools and newly developed shell/perl scripts.
Analyses of the PRO endpoints were conducted using available data from all eligible patients; data collected until study discontinuation were analysed according to the cohort (exenatide BID or insulin) that patients were placed in at baseline ("initiators" analysis).
As the process of assigning a mosquito breeding site abundance index to each cell does not rely on fitting-to-data, validation of this methodology was conducted using available trapping data from Cairns for the years 2006 2013, kindly provided by Scott Ritchie James Cookk University and Peter Cook Monash Universityty).
Moreover, the developed method was economical and can be conducted using only basic molecular tools that are available in most laboratories.
The simulations were conducted using commercially available transient analysis software.
Experiments were conducted using publicly available benchmark data sets.
Based on the procedure, an initial reliability analysis is conducted using currently available data.
The impact testing machine was equipped and experiments were conducted using the available facilities and data were also collected by a data-logger.
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