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They can be conducted in random population-based samples and frequently are cross-sectional or birth cohort studies (Joffe 2000; Joffe and Li 1994; Karmaus et al. 1999; Sallmén et al. 1995; Schaumburg and Boldsen 1992; Schaumburg and Olsen 1989; Thonneau et al. 1999), thereby overcoming the problem that only women who eventually conceived are included.
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Mixed meal tests were conducted in random order using a randomization list generated in StatsDirect 4 (StatsDirect Ltd ,UK), between 48 h and 2 weeks apart.
Duplicate measurements were made for each condition, so that a total of 48 tests were conducted, in random order.
Subsequently, ethanol and water sessions were conducted in random order across training days with the constraint that all rats received a total of 10 ethanol and 10 water sessions.
The ultrasonic treatments were conducted in random to minimize systematic errors [17].
The first interval was always conducted at 0% BWS; thereafter, intervals at 10, 20, and 30% BWS were conducted in random order.
To avoid systematic bias due to muscular fatigue, contraction direction and intensities were conducted in random order, sustained for approximately five seconds, and separated by 2-min rest periods.
Thus, each male received six experimental trials, which were conducted in random order.
Such effect modification could lead to nondifferential misclassification bias (trials are conducted in random order), resulting in an underestimation of the true effect that pollutant exposure has on the induction of inflammation in humans.
However this is unlikely to systematically differ between mixed meal tests (which were conducted in random order) and a longer period without medication might have made results less applicable to clinical practice.
All sessions will be conducted in the randomized order and random sequence of study sessions will be generated using a computer, though patient's existing dialysis schedule will not be disturbed.
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