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The difference in costs of the intervention group and usual care group will be computed using bootstrapping techniques.
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The significance value of signal flows at each node is computed using bootstrapping.
The confidence intervals (95%) were computed using bootstrapping method.
The variance was computed using bootstrapping (1000 replicates).
Standard errors of those regression coefficients were computed using bootstrapping with the R-package "boot" [ 16].
Both confidence intervals are computed using bootstrap with a thousand replications.
c CIs were computed using bootstrap weights to account for the complex sampling design of the National Longitudinal Survey of Children and Youth.
In order to obtain the costs per treatment responder and the costs per QALY gained, the incremental cost-effectiveness ratio (ICER) will be computed using the bootstrap method.
Data are presented as r (95% CI) with the 95% CI computed using bootstrapping.
Data are presented as r [95% confidence interval (CI)] with the 95% CI computed using bootstrapping.
To test if the differences of AUCs based on the different combination systems were statistically significant, we computed a one-sided p value for the hypothesis that the difference between the AUC of the two systems was not equal to 0. The tests were computed using a bootstrapping method [ 42, 43].
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