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92 Thus, the ability of IER to enhance BDNF signaling and protect neurons against injury may be compromised with aging.
The innate immune response capacity of macrophages appears to be compromised with aging (Sebastian et al., 2009), potentially contributing to senescent cell accumulation in old age.
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Given that 5-HT anorectic efficacy is maintained with aging, we surmised that it is POMC basal tone that is compromised with aging, not the 5-HT2CR and POMC neuroanatomical appetitive machinery.
Our research groups have contributed to the field of muscle aging by demonstrating that specific aspects of the excitation-contraction coupling (ECC) process are compromised with age [ 11, 12].
The HA-mediated CD44-EGFR pathway was found to be compromised with in vitro aging, through loss of EGFR expression and a reduced movement of CD44 throughout the cellular membrane.
Myocardial function and intracellular Ca2+ handling were compromised with advanced aging; the effects were accentuated by ALDH2.
It has been suggested that the immune response to novel antigens is compromised with advancing age.
The SPPB includes assessments of balance, gait speed, and lower extremity strength, and those functions are compromised with the intersection of MS and aging.
38 Therefore, cognitive abilities are compromised with depression and anxiety.
Given that ARC POMC neuron function is diminished with age, we next sought to determine whether 5-HT compound anorectic potency is thereby compromised with aging.
Dermal and epidermal homeostasis is compromised in aging and a variety of disease processes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com