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Moreover, active MMP-9 can be completely neutralized by protease inhibitors such as tissue inhibitors of metalloproteinases (TIMPs) [ 42].
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However, whereas lyssavirus genotypes containing the residue K226 within antigenic site I were completely neutralized by mAb 62-71-3, lyssaviR226showedaining R226 showediminisheded neutralization, and no 100% neutralizing titer could be defined for this point mutant (Fig. 6 C).
Although lyssaviruses containing the antigenic site I residue K226 (lysine) were completely neutralized by mAb 62-71-3, lyssaviruses conthening the residue R226 (arginine) demonstrated diminished neutralization.
On the other hand, Stx2 is completely neutralized by anti-Stx2c antiserum, whereas Stx2c is only partially neutralized by Stx2 antiserum [10].
We previously determined that the bactericidal activity of a solution containing 20 mM MGO was completely neutralized by conversion to SLG [14].
Again, this anti-inflammatory effect was completely neutralized by Bevacizumab treatment, thus implying that NPC-secreted VEGF was important for both pro-angiogenic and immune regulatory effects [ 105].
The H5 pseudotypes were completely neutralized by the H5 sheep sera (NIBRG-14 H5N1) at a 1 : 1280 dilution but not by the H7 antisera (A/African starling/England/983/1979) whilst the H7 pseudotype was completely neutralized by the H7 antisera at a 1 : 1280 dilution but not by the H5 sheep sera.
If the unknown virus registers a titre of between 103 and 105 TCin50 in the presence of rinderpest-negative serum and is completely neutralized by the rinderpest-positive serum, the diagnosis of rinderpest is confirmed.
The angiogenic activity triggered by activated murine peritoneal macrophages is completely neutralized by a polyclonal antibody to TNF-α, implying that immunological features are common to both TNF-α and the protein responsible for macrophage-derived angiogenic activity [ 30].
Still, like in previous works, the increase of glycerol formation was accompanied with high levels of oxidized by-products like acetic acid, acetoin and acetaldehyde, and this effect could not be completely neutralized with additional genetic modifications.
And yet the body in Mr. Pearlstein's pictures — usually young, healthy and female — could not be completely neutralized.
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