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This cleavage could be completely abrogated using z-VAD-fmk, an irreversible caspase inhibitor.
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Therefore, WASP expression in homozygous clones should be completely abrogated.
However, protein adsorption could not be completely abrogated, even at high PEG coupling concentration.
The increased O2- generation could be completely abrogated by apocynin (Fig. 6b).
Indeed, we found cathepsin K activity to be completely abrogated in the presence of rapamycin (Fig. 5b).
These effects were completely abrogated by the use of a Notch4 blocking antibody [ 90].
Binding of Natalizumab-FITC was completely abrogated in the presence of a 10 fold excess of unlabeled Natalizumab, which was used as a negative control in each donor to calculate the specific fluorescence index (SFI).
Reporter gene expression was completely abrogated in a competitive manner by the presence of excess FK506 or MTX, respectively.
The deoxygenation-induced cation conductance (sometimes termed Psickle) was partially inhibited, whilst deoxygenation-induced exposure of phosphatidylserine was completely abrogated.
This apoptosis was completely abrogated when monocytes were pretreated with a specific caspase-1 inhibitor, YVADcmk.
However when CFTRinh172 is added, the decrease in inflammation induced by cAMP is completely abrogated.
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