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This suggests that the scanning state should be competent for interaction with the SRP receptor, potentially permitting targeting while the TMD is still inside the tunnel.
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Altogether the results indicate that neutral membranes are able to interact with Penetratin which confirms that the phosphate negatively charged groups exposed on the external leaflet of plasma membrane are competent for interaction with the basic peptide.
Observations and interactions during the training workshops identified some recruited youth that were not judged to be competent for the role of youth mentor as a result of difficulty in interpersonal interactions or impatience with working with children.
Experimental data show that zwitterionic lipid headgroups take part in the interaction with Penetratin suggesting that the external leaflet lipids of cells plasma membrane are competent for peptide interaction in the absence of net negative charges.
We speculate that only oligomeric forms of PAPC transmembrane domains are competent for its interactions with FLRT3 transmembrane domain.
Early experiments with CTX inhibition of the BK channel revealed that CTX binds to the extracellular surface of the channel with a 1 1 channel:toxin stoichiometry, that both the open and closed states of the channel are competent for toxin binding, and that electrostatic interactions play an important role in enhancing the toxin's affinity (Anderson et al., 1988).
We conclude that despite asymmetry in the ligand-receptor interaction, both sides are competent for signaling, and appear to signal equally.
Thus, the binding energy of the RNA-protein interaction likely stabilizes a strained conformation that is competent for ATP hydrolysis.
In our assays SIM-interaction mutants of both SUMO1 and SUMO2 are competent for modification of CtBP when driven by over-expression of Ubc9, suggesting that in the absence of Pc2 SIM-SUMO interactions do not contribute to CtBP modification.
It can be concluded that the combined model is competent for numerical simulation of the atmospheric plasma spraying.
The system works in real time, which is competent for most engineering measurement requirements.
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